The invention of aspirin by Gerhardt was abandoned right up until Felix Hoffman, a German chemist, rediscovered it in 1887 and uncovered of its special property of diminished gastrointestinal irritation compared with salicylic acid. Shortly afterward, "aspirin" was patented by Bayer in 1889 as a fresh analgesic surprise drug. The https://www.directivepublications.org/allergy-and-clinical-immunology/