Caloric restriction and intermittent fasting have also been proven to directly inhibit the mTOR pathway, therefore relieving the inhibition from the autophagy pathway to lead to apoptosis. Conversely, intermittent fasting is demonstrated to activate AMPK, which inhibits mTOR from halting autophagy in swiftly escalating cancer cells. At last, the https://directivepublications.org/world-journal-of-clinical-cancer-research/