Epidural clonidine utilised as an adjunct to regional anesthetics has a few distinctive mechanisms of action. To start with, the stimulation of alpha-2-receptors from the dorsal horn reduces pain transmission. Next, clonidine could potentially cause regional vasoconstriction that limits vascular removal of regional epidural anesthetics. Applies to clonidine: oral https://pietm516jcu4.bloggerchest.com/profile