In eukaryotic cells an uncleavable ubiquitin moiety conjugated to the N-terminus of a protein signals the degradation of the fusion protein via the proteasome-dependent ubiquitin fusion degradation (UFD) pathway. In yeast the molecular mechanism of the UFD pathway has been well characterized. Recently the human E3 ubiquitin-protein ligase TRIP12 was connected with the UFD pathway. but... https://sdskqspt7dqwbo.collectblogs.com/79707240/de-capability-approach-als-normatief-evaluatief-kader-voor-sociale-interventies-kwalitatief-onderzoek-in-india-met-inzichten-voor-de-vlaamse-en-nederlandse-praktijk