The conclusion that MMPs mediate the breaking down of sort II collagen and that aggrecan is destroyed by similar metalloproteinases termed adamalysins with thrombospondin motifs (ADAMTSs) is supported by a considerable overall body of evidence [10]. As such, osteoarthritis occurs and an infection or injury for the joints can accelerate the https://www.theorthopaedicandpainpractice.com/all-you-need-to-know-about-osteoarthritis/