Pentobarbital will decrease the level or effect of doravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. pentobarbital will decrease the level or effect of zonisamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. Acting as both a sedative and a hypnotic, pentobarbital can be prescribed for the short-term treatment of insomnia. https://xyzbookmarks.com/story20129449/esamina-la-relazione-sulla-pentobarbital-vs-phenobarbital