Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors in the central anxious process, conolidine modulates alternate molecular targets. A Science Innovations review found that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By influencing https://stephenxhpwc.ziblogs.com/39122709/considerations-to-know-about-alternative-natural-pain-relief-to-replace-traditional-painkillers